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(pathology) A rare genetic disorder characterized by abnormal development of the spine and cartilage/bone, leading to skeletal abnormalities such as short stature, spinal malformations, and metaphyseal bone changes; it may also be associated with immune system dysfunction, including increased susceptibility to autoimmune disease.
Related-word data is supplemented by the Datamuse API. Datamuse results are suggestions, not automatic replacements.