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Pronunciation varies by accent · adjective
(idiomatic) vicious; violent; full of strength and power.
a tooth-and-nail fight
a tooth-and-nail battle
a tooth-and-nail scrap
a tooth-and-nail debate
They fought tooth-and-nail
Use tooth-and-nail when its meaning, tone and grammar fit the full sentence. A synonym is not always a direct replacement.
Tooth-and-nail means (idiomatic) vicious; violent; full of strength and power.
The closest synonym depends on the sentence and intended sense.
The opposite depends on the specific sense.
a tooth-and-nail fight
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