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/əˌkæn.θoʊˌkɜɹ.ə.toʊˈdɝ.mi.ə/ · noun
(pathology) A thickening of the horny portion of the skin on the hand palms and soles of the feet..
Use acanthokeratodermia when its meaning, tone and grammar fit the full sentence. A synonym is not always a direct replacement.
Acanthokeratodermia means (pathology) A thickening of the horny portion of the skin on the hand palms and soles of the feet..
The closest synonym depends on the sentence and intended sense.
The opposite depends on the specific sense.
Use acanthokeratodermia where its definition matches the intended context.
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