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/ˈæ.maɪd/ · noun
(organic chemistry) Any derivative of an oxoacid in which the hydroxyl group has been replaced with an amino or substituted amino group; especially such derivatives of a carboxylic acid, the carboxamides or acid amides.
Use amide when its meaning, tone and grammar fit the full sentence. A synonym is not always a direct replacement.
Amide means (organic chemistry) Any derivative of an oxoacid in which the hydroxyl group has been replaced with an amino or substituted amino group; especially such derivatives of a carboxylic acid, the carboxamides or acid amides.
The closest synonym depends on the sentence and intended sense.
The opposite depends on the specific sense.
Use amide where its definition matches the intended context.
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