Checking saved dictionary data and trusted language sources. This will stop automatically if a source does not respond.
/ˈkætəˌplɛksi/ · noun
(medicine) An abrupt loss of muscle tone, sometimes associated with narcolepsy..
Narcolepsy has been associated with the human leukocyte antigen (HLA) system, a 4-megabase region of chromosome 6, which is divided into three subregions: class I, class II, and class III. Class II HLA antigens have been strongly associated with autoimmune diseases. The class II antigen, DQB1*0602, has been associated with narcolepsy. Most (90%-100%) patients with narcolepsy/cataplexy across all ethnic groups have this allele. In addition, 35% to 56% of patients who have narcolepsy without cataplexy also have this allele. However, 20% of the normal population also has the allele, reducing its usefulness in diagnostic testing.
Use cataplexy when its meaning, tone and grammar fit the full sentence. A synonym is not always a direct replacement.
Cataplexy means (medicine) An abrupt loss of muscle tone, sometimes associated with narcolepsy..
The closest synonym depends on the sentence and intended sense.
The opposite depends on the specific sense.
Narcolepsy has been associated with the human leukocyte antigen (HLA) system, a 4-megabase region of chromosome 6, which is divided into three subregions: class I, class II, and class III. Class II HLA antigens have been strongly associated with autoimmune diseases. The class II antigen, DQB1*0602, has been associated with narcolepsy. Most (90%-100%) patients with narcolepsy/cataplexy across all ethnic groups have this allele. In addition, 35% to 56% of patients who have narcolepsy without cataplexy also have this allele. However, 20% of the normal population also has the allele, reducing its usefulness in diagnostic testing.
FreeDictionaryAPI.com / Wiktionary · Original source · CC BY-SA 4.0
Dictionary data is provided by FreeDictionaryAPI.com and sourced from Wiktionary under its stated license.