ENGLISH DICTIONARY

Cytokine

Definition, Meaning & Examples

Pronunciation /ˈsaɪ.tə(ʊ)(ˌ)kaɪn/ · Part of speech noun

Quick meaning: Cytokine is a noun meaning (biochemistry, immunology) Any of various small regulatory proteins that regulate the cells of the immune system.

Meaning

(biochemistry, immunology) Any of various small regulatory proteins that regulate the cells of the immune system.

Example Sentences

A fundamental feature expressed by the vast majority of cytokines is a profound immunomodulatory activity. Many cytokines, presently available in pure recombinant form, modify bone cell metabolism.
Surprisingly, mTOR inhibitors displayed little inhibitory efficacy regarding receptor modulation and cytokine production which may be clinically relevant in terms of the risk of underimmunosuppression with this class of drugs.
The cytokines are generally considered to be a group of peptides secreted by cells of the immune system such as macrophages, lymphocytes and T cells, although the same peptides may also be secreted by non-immune cells such as neurological tissues and adipocytes.
Thus, in the case of viral infection, mechanisms of resistance would be threefold, namely, interferon production, the immune response, including both antibody and lymphokine production, and the generation of lymphokine-like substances by the infected cells themselves. These latter substances have been defined as cytokines.

Word Forms

Related Words

Related dictionary entries include interleukin, adipokine, monokine, lymphokine, interferon, chemokine.

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Sources & Attribution

FreeDictionaryAPI.com / Wiktionary · Original source · CC BY-SA 4.0

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