What does depart mean?
Depart means (intransitive) To leave..
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/dɪˈpɑːt/ · verb
(intransitive) To leave..
[…] he that hath no ſtomacke to this feaſt, Let him depart, […]
The glory is departed from Israel.
With very little excuse for departing so abruptly, Ralph left him, […]
She came in now, but to the closet; from it she took a simple skirt and blouse. Picking up her underclothing she departed, obviously to dress somewhere else.
The government maintains that if its regulations are too stiff, British bankers will leave the country. It's true that they have been threatening to depart in droves, but the obvious answer is: "Sod off then."
And soo she receyued hym vpon suffysaunt seurte / so alle her hurtes were wel restored of al that she coude complayne / and thenne he departed vnto the Courte of kyne Arthur / and there openly the reed knyghte of the reed laundes putte hym in the mercy of syre Launcelot and syr Gawayne
Elizabeth saw her friend depart for Port-Breedy, […]
Distant acclamations, words of command yelled out, and a roll of drums on the jetty greeted the departing general.
Use depart when its meaning, tone and grammar fit the full sentence. A synonym is not always a direct replacement.
Depart means (intransitive) To leave..
Common synonyms include leave, die, deviate, digress.
Possible antonyms include arrive, come, stay, live.
[…] he that hath no ſtomacke to this feaſt, Let him depart, […]
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