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/dɪsəˈfɛkt/ · verb
(transitive) To cause a loss of affection, sympathy or loyalty in; to alienate or estrange..
Use disaffect when its meaning, tone and grammar fit the full sentence. A synonym is not always a direct replacement.
Disaffect means (transitive) To cause a loss of affection, sympathy or loyalty in; to alienate or estrange..
Common synonyms include alienate, estrange, alien.
The opposite depends on the specific sense.
Use disaffect where its definition matches the intended context.
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