Downsies

Quick meaning: Downsies is a noun meaning (slang, rare) Synonym of tranquilizers (“drugs used to reduce anxiety or tension”).

Meaning

(slang, rare) Synonym of tranquilizers (“drugs used to reduce anxiety or tension”).

Example Sentences

Sylvia may not take drugs, but Kim was very into pills—upsies and downsies and in-betweensies.

Girls seek release through drinking and pills and dexies and upsies and downsies. Whatever. I haven’t had to.

The Rolling Stones cut a record called “Mother’s Little Helpers.’[’] An innocuous title? You bet it was, but the lyrics revealed that “Mother’s Little Helpers” are the “upsies and downsies” that mom takes to get her through the day. The “upsies” are the pep pills she takes when she wakes up and the “downsies” are the tranquilizers she takes before going to bed.

Synonyms for downsies

Depending on context, synonyms include tranquilizers.

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