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/ˈɛˌstɹoʊn/ · noun
(American spelling, biochemistry, steroids, pharmacology) A natural estrogenic hormone that is a ketone C₁₈H₂₂O₂ found in the body chiefly as a metabolite of and less potent than estradiol, that is also secreted especially by the ovaries, and that is used to treat various conditions (such as ovarian failure and menopausal symptoms) relating to estrogen deficiency..
Use estrone when its meaning, tone and grammar fit the full sentence. A synonym is not always a direct replacement.
Estrone means (American spelling, biochemistry, steroids, pharmacology) A natural estrogenic hormone that is a ketone C₁₈H₂₂O₂ found in the body chiefly as a metabolite of and less potent than estradiol, that is also secreted especially by the ovaries, and that is used to treat various conditions (such as ovarian failure and menopausal symptoms) relating to estrogen deficiency..
Common synonyms include theelin, oestrone.
The opposite depends on the specific sense.
Use estrone where its definition matches the intended context.
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