What does histotope mean?
Histotope means The portion of an antigen that reacts with or binds to a T-cell..
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Pronunciation varies by accent · noun
The portion of an antigen that reacts with or binds to a T-cell..
Thus, a mutation affecting the structure of a class II molecule changes the co-recognition specificity of a histotope on the APC of the mutant.
However, this experiment by itself did not distinguish whether the change was in the desetope, which is the most straightforward interpretation, or in the histotope.
First, during ontogeny, T cells are positively selected by recognition of the histotope and then negatively selected by a tolerance mechanism or vice versa.
Use histotope when its meaning, tone and grammar fit the full sentence. A synonym is not always a direct replacement.
Histotope means The portion of an antigen that reacts with or binds to a T-cell..
The closest synonym depends on the sentence and intended sense.
The opposite depends on the specific sense.
Thus, a mutation affecting the structure of a class II molecule changes the co-recognition specificity of a histotope on the APC of the mutant.
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