ENGLISH DICTIONARY

Histotope

Definition, Meaning & Examples

Part of speech noun

Quick meaning: Histotope is a noun meaning The portion of an antigen that reacts with or binds to a T-cell.

Meaning

The portion of an antigen that reacts with or binds to a T-cell.

Example Sentences

Thus, a mutation affecting the structure of a class II molecule changes the co-recognition specificity of a histotope on the APC of the mutant.
First, during ontogeny, T cells are positively selected by recognition of the histotope and then negatively selected by a tolerance mechanism or vice versa.
However, this experiment by itself did not distinguish whether the change was in the desetope, which is the most straightforward interpretation, or in the histotope.

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