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Pronunciation varies by accent · noun
(radiotherapy) An especially highly divided form of fractionation: the division of a total dose of radiation into many small fractions..
Treatment with several doses per day offers the prospect of a significant therapeutic gain using readily available low LET beams. These regimens can be classified as either accelerated fractionation or hyperfractionation according to their rationales. With accelerated fractionation a conventional number of dose fractions is delivered in a significantly shortened overall treatment time in order to reduce the opportunity for tumor cell regeneration during treatment. With hyperfractionation, on the other hand, a large number of significantly reduced dose fractions is used to give a greater total dose in a conventional overall treatment time.
Use hyperfractionation when its meaning, tone and grammar fit the full sentence. A synonym is not always a direct replacement.
Hyperfractionation means (radiotherapy) An especially highly divided form of fractionation: the division of a total dose of radiation into many small fractions..
The closest synonym depends on the sentence and intended sense.
The opposite depends on the specific sense.
Treatment with several doses per day offers the prospect of a significant therapeutic gain using readily available low LET beams. These regimens can be classified as either accelerated fractionation or hyperfractionation according to their rationales. With accelerated fractionation a conventional number of dose fractions is delivered in a significantly shortened overall treatment time in order to reduce the opportunity for tumor cell regeneration during treatment. With hyperfractionation, on the other hand, a large number of significantly reduced dose fractions is used to give a greater total dose in a conventional overall treatment time.
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