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Pronunciation varies by accent · noun
An abnormally increased responsiveness, especially that due to hypersensitivity or hyperreactivity..
Use hyperresponsiveness when its meaning, tone and grammar fit the full sentence. A synonym is not always a direct replacement.
Hyperresponsiveness means An abnormally increased responsiveness, especially that due to hypersensitivity or hyperreactivity..
The closest synonym depends on the sentence and intended sense.
The opposite depends on the specific sense.
Use hyperresponsiveness where its definition matches the intended context.
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