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Pronunciation varies by accent · noun
(obsolete) The quality of being indefatigable; tirelessness..
The Arabian Geographers[…] holding themselves not to be inferior (as indeed they were not) either to the Indefatigation or Skill of the Greek Geographers, they hoped to have the beginning of Longitude taken from them
Use indefatigation when its meaning, tone and grammar fit the full sentence. A synonym is not always a direct replacement.
Indefatigation means (obsolete) The quality of being indefatigable; tirelessness..
The closest synonym depends on the sentence and intended sense.
The opposite depends on the specific sense.
The Arabian Geographers[…] holding themselves not to be inferior (as indeed they were not) either to the Indefatigation or Skill of the Greek Geographers, they hoped to have the beginning of Longitude taken from them
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