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/əʊˈmɛp.ɹə.zəʊl/ · noun
(pharmacology) A substituted benzimidazole (trademark Losec, Prilosec) which is a proton pump inhibitor and inhibits secretion of gastric acid, being given orally in the treatment of ulcers and gastroesophageal reflux; 5-methoxy-2-(4-methoxy-3,5-dimethyl-2-pyridylmethylsulfinyl)benzimidazole, C₁₇H₁₉N₃O₃S..
2001: The first successful drug of this class was omeprazole (sold under the trade name Losec®), and it helped to change the medium-sized Swedish pharmaceutical company Astra, which discovered it, into a major player in the pharmaceutical industry. — Leslie Iversen, Drugs: A Very Short Introduction (Oxford 2001, p. 46)
Use omeprazole when its meaning, tone and grammar fit the full sentence. A synonym is not always a direct replacement.
Omeprazole means (pharmacology) A substituted benzimidazole (trademark Losec, Prilosec) which is a proton pump inhibitor and inhibits secretion of gastric acid, being given orally in the treatment of ulcers and gastroesophageal reflux; 5-methoxy-2-(4-methoxy-3,5-dimethyl-2-pyridylmethylsulfinyl)benzimidazole, C₁₇H₁₉N₃O₃S..
The closest synonym depends on the sentence and intended sense.
The opposite depends on the specific sense.
2001: The first successful drug of this class was omeprazole (sold under the trade name Losec®), and it helped to change the medium-sized Swedish pharmaceutical company Astra, which discovered it, into a major player in the pharmaceutical industry. — Leslie Iversen, Drugs: A Very Short Introduction (Oxford 2001, p. 46)
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