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/pɒliˌtɑksɪkəʊˈmeɪniə/ · noun
The addiction to multiple drugs or other intoxicating substances..
Use polytoxicomania when its meaning, tone and grammar fit the full sentence. A synonym is not always a direct replacement.
Polytoxicomania means The addiction to multiple drugs or other intoxicating substances..
The closest synonym depends on the sentence and intended sense.
The opposite depends on the specific sense.
Use polytoxicomania where its definition matches the intended context.
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