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/pɑks/ · noun
A disease characterized by skin eruptions (especially purulent ones) that may leave pockmarks..
a pox on all their houses
A pox on him, he's a cat still.
Jack had a moſt ſcandalous tongue, and perſuaded Peg that all mankind, beſides himſelf, were pox'd by that ſcarlet-faced whore, †Signiora Bubonia. “As for his brother Lord Peter, the tokens were evident on him, blotches, ſcabs, and the corona. […]”
Use pox when its meaning, tone and grammar fit the full sentence. A synonym is not always a direct replacement.
Pox means A disease characterized by skin eruptions (especially purulent ones) that may leave pockmarks..
Common synonyms include syphilis, syph.
The opposite depends on the specific sense.
a pox on all their houses
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