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Pronunciation varies by accent · adjective
(pathology) Relating to the early stage of a disease, in which symptoms are not yet manifest.
The premanifest stage of HD (pre-HD) [5 ] provides an unprecedented opportunity to characterize deficits and ultimately encapsulate sensitive markers of disease progression from premanifest to symptomatic stages for potential use in clinical interventions [4 ,6 ,7 ].
Use premanifest when its meaning, tone and grammar fit the full sentence. A synonym is not always a direct replacement.
Premanifest means (pathology) Relating to the early stage of a disease, in which symptoms are not yet manifest.
The closest synonym depends on the sentence and intended sense.
The opposite depends on the specific sense.
The premanifest stage of HD (pre-HD) [5 ] provides an unprecedented opportunity to characterize deficits and ultimately encapsulate sensitive markers of disease progression from premanifest to symptomatic stages for potential use in clinical interventions [4 ,6 ,7 ].
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