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Pronunciation varies by accent · adjective
(genetics) Prior to the formation of nucleosomes; relating to prenucleosomes.
Since the three histone-fold domain amino acids are located at the surface of the α-helix 2 domain that is responsible for the formation of H3-H4 dimers and accessible in prenucleosomal complexes, it has been suggested that the specificity associated with these amino acid positions derives from interactions with different assembly or post-translational-modification machineries.
Use prenucleosomal when its meaning, tone and grammar fit the full sentence. A synonym is not always a direct replacement.
Prenucleosomal means (genetics) Prior to the formation of nucleosomes; relating to prenucleosomes.
The closest synonym depends on the sentence and intended sense.
The opposite depends on the specific sense.
Since the three histone-fold domain amino acids are located at the surface of the α-helix 2 domain that is responsible for the formation of H3-H4 dimers and accessible in prenucleosomal complexes, it has been suggested that the specificity associated with these amino acid positions derives from interactions with different assembly or post-translational-modification machineries.
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