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/ˌspʌɪ.ɹən.ə(ʊ)ˈlæk.təʊn/ · noun
(pharmacology) A steroid drug which acts as an antimineralocorticoid (for which purpose it is used in the treatment of certain types of edema and hypertension) and an antiandrogen (for which purpose it is used as part of some types of hormone therapy, especially for transgender women)..
Use spironolactone when its meaning, tone and grammar fit the full sentence. A synonym is not always a direct replacement.
Spironolactone means (pharmacology) A steroid drug which acts as an antimineralocorticoid (for which purpose it is used in the treatment of certain types of edema and hypertension) and an antiandrogen (for which purpose it is used as part of some types of hormone therapy, especially for transgender women)..
Common synonyms include spiro, aldactone.
The opposite depends on the specific sense.
Use spironolactone where its definition matches the intended context.
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