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(surgery, chiefly historical) A surgical operation involving cutting into a lobe of a body organ, specifically (neurosurgery), a procedure, now largely disused, involving severing connections between the prefrontal cortex and the thalamic region of the frontal lobe of the brain to treat certain mental illnesses.
Related-word data is supplemented by the Datamuse API. Datamuse results are suggestions, not automatic replacements.