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Pronunciation varies by accent · noun
(organic chemistry) A derivative of a pyridone in which the carbonyl oxygen atom is substituted by one of sulfur.
Thiopropyl Sepharose™ 6B (GE Healthcare) has been used widely over several decades to reversibly bind biological molecules containing the sulfhydryl groups—the 2-thiopyridyl disulphide group of the sepharose matrix reacts with a molecule containing a free thiol to form a mixed disulfide; during the reaction thiopyridone is formed while the bound target molecule is released by addition of a reducing agent.
Use thiopyridone when its meaning, tone and grammar fit the full sentence. A synonym is not always a direct replacement.
Thiopyridone means (organic chemistry) A derivative of a pyridone in which the carbonyl oxygen atom is substituted by one of sulfur.
The closest synonym depends on the sentence and intended sense.
The opposite depends on the specific sense.
Thiopropyl Sepharose™ 6B (GE Healthcare) has been used widely over several decades to reversibly bind biological molecules containing the sulfhydryl groups—the 2-thiopyridyl disulphide group of the sepharose matrix reacts with a molecule containing a free thiol to form a mixed disulfide; during the reaction thiopyridone is formed while the bound target molecule is released by addition of a reducing agent.
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