Chaperome

Quick meaning: Chaperome is a noun meaning (biochemistry) All the proteins called chaperones that assist in the folding of misfolded proteins in an organism, and other functions.

Meaning

(biochemistry) All the proteins called chaperones that assist in the folding of misfolded proteins in an organism, and other functions.

Example Sentences

Redundancy in the chaperome networks is evidenced in a number of large-scale investigations where individual chaperomes were either genetically deleted or pharmacologically inhibited.

In another study, Brehme et al. have examined the chaperome in C. elegans and human. They find that chaperome expression is dramatically affected in human brain aging. At the same time, chaperome dynamics are associated with aging and neurodegenerative diseases.

The nature of the epichaperome, therefore, which presents as stable, multi-partner complexes affected by strong interactions as opposed to other cellular forms of chaperomes present in dynamic complexes of weak interactions, provide opportunities for its detection through small molecules [...].

To date data exist to describe the organ-specific distribution and function of many chaperones, but less is known about their cell-type specificity and how this changes in response to different stressors. A systems view on the entire "chaperome" would be essential to understand chaperone function under basal and stress conditions.

Word Forms

• chaperomes

Related Words

Related dictionary entries include chaperone, chaperonin, chaperokine, superchaperone, cochaperone, multichaperone.

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