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Pronunciation varies by accent · noun
A particular kind of molecular chaperone that assists the non-covalent folding of proteins in an ATP-dependent manner. Holdases bind to protein folding intermediates to prevent their aggregation but without directly refolding them..
As a part of that network, holdase chaperones are able to communicate with other chaperones in the network, to achieve refolding of misfolded clients.
Use holdase when its meaning, tone and grammar fit the full sentence. A synonym is not always a direct replacement.
Holdase means A particular kind of molecular chaperone that assists the non-covalent folding of proteins in an ATP-dependent manner. Holdases bind to protein folding intermediates to prevent their aggregation but without directly refolding them..
The closest synonym depends on the sentence and intended sense.
The opposite depends on the specific sense.
As a part of that network, holdase chaperones are able to communicate with other chaperones in the network, to achieve refolding of misfolded clients.
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